Thomas J Rutherford Selected Research

hI-con1

10/2011	Tissue factor expression in ovarian cancer: implications for immunotherapy with hI-con1, a factor VII-IgGF(c) chimeric protein targeting tissue factor.
6/2011	Expression of tissue factor in adenocarcinoma and squamous cell carcinoma of the uterine cervix: implications for immunotherapy with hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor.

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Thomas J Rutherford Research Topics

Disease

42	Neoplasms (Cancer) 01/2022 - 01/2003
22	Ovarian Neoplasms (Ovarian Cancer) 01/2020 - 04/2007
22	Carcinoma (Carcinomatosis) 01/2018 - 09/2005
9	Ovarian Epithelial Carcinoma 01/2016 - 09/2003
6	Papillary Carcinoma 07/2013 - 01/2010
5	Ovarian Diseases (Ovarian Disease) 12/2015 - 07/2009
4	Endometrial Neoplasms (Endometrial Cancer) 07/2015 - 02/2010
4	Carcinosarcoma 01/2015 - 09/2010
4	Uterine Cervical Neoplasms (Cancer of the Cervix) 12/2011 - 07/2009
3	Disease Progression 05/2011 - 11/2007
2	Pre-Eclampsia (Preeclampsia) 04/2024 - 01/2012
2	Fallopian Tube Neoplasms 01/2017 - 06/2015
2	Ascites 02/2015 - 07/2010
2	Endometrioid Carcinoma 12/2011 - 02/2010
1	Nausea 01/2023
1	Constipation 01/2023
1	Vomiting 01/2023
1	Foreign Bodies (Foreign Body) 01/2022
1	Endometrial Stromal Sarcoma 01/2019
1	Fanconi Anemia (Fanconi's Anemia) 01/2016
1	Leukemia 01/2016
1	Frailty 06/2015
1	Dementia (Dementias) 06/2015
1	Bites and Stings (Sting) 02/2015
1	Hypoxia (Hypoxemia) 01/2014
1	Overweight 09/2012
1	Body Weight (Weight, Body) 09/2012

Drug/Important Bio-Agent (IBA)

14	PlatinumIBA 01/2016 - 09/2005
12	Proteins (Proteins, Gene)FDA Link 04/2024 - 07/2009
10	Paclitaxel (Taxol)FDA LinkGeneric 01/2016 - 11/2007
8	Messenger RNA (mRNA)IBA 12/2011 - 11/2007
7	Monoclonal AntibodiesIBA 05/2012 - 07/2009
5	taxaneIBA 06/2015 - 04/2009
5	Epithelial Cell Adhesion MoleculeIBA 02/2015 - 07/2009
5	TubulinIBA 01/2014 - 06/2009
5	epothilone B (EPO906)IBA 01/2014 - 10/2010
4	Peptides (Polypeptides)IBA 12/2015 - 01/2009
4	Interleukin-2 (IL2)IBA 12/2011 - 12/2010
3	RNA (Ribonucleic Acid)IBA 01/2016 - 07/2009
3	Carboplatin (JM8)FDA LinkGeneric 01/2016 - 10/2006
3	Clostridium enterotoxinIBA 12/2015 - 07/2010
3	Claudin-3IBA 12/2015 - 07/2010
3	Biomarkers (Surrogate Marker)IBA 01/2014 - 02/2010
3	adecatumumabIBA 12/2010 - 01/2010
2	MicroRNAs (MicroRNA)IBA 01/2018 - 09/2010
2	Cisplatin (Platino)FDA LinkGeneric 01/2016 - 05/2011
2	DNA (Deoxyribonucleic Acid)IBA 01/2016 - 02/2013
2	Antineoplastic Agents (Antineoplastics)IBA 01/2016 - 07/2010
2	Fluorescein-5-isothiocyanate (FITC)IBA 12/2015 - 07/2010
2	Bevacizumab (Avastin)FDA Link 06/2015 - 01/2012
2	ixabepilone (BMS 247550)FDA Link 06/2015 - 07/2013
2	Immunoconjugates (Immunoconjugate)IBA 01/2015 - 10/2014
2	Epothilones (Epothilone)IBA 07/2013 - 07/2013
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 07/2013 - 07/2013
2	Complement System Proteins (Complement)IBA 05/2012 - 10/2011
2	Claudin-4IBA 12/2011 - 07/2010
2	Small Interfering RNA (siRNA)IBA 12/2011 - 10/2011
2	ParaffinIBA 11/2011 - 09/2010
2	Thromboplastin (Tissue Factor)IBA 10/2011 - 06/2011
2	hI-con1IBA 10/2011 - 06/2011
2	A-factor (Streptomyces)IBA 10/2011 - 06/2011
2	Rituximab (Mabthera)FDA Link 07/2011 - 06/2011
2	phenoxodiolIBA 05/2011 - 04/2009
2	Interferon-gamma (Interferon, gamma)IBA 02/2009 - 01/2009
2	EpitopesIBA 02/2009 - 01/2009
1	Proto-Oncogene Proteins c-mdm2IBA 04/2024
1	Opioid Analgesics (Opioids)IBA 01/2023
1	purified rayonIBA 01/2022
1	Aromatase InhibitorsIBA 01/2019
1	Progestins (Progestagens)IBA 01/2019
1	Mitomycin (Mitomycin-C)FDA LinkGeneric 01/2016
1	3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine)IBA 01/2016
1	Fluorescent Dyes (Fluorescent Probes)IBA 12/2015
1	ErbB Receptors (EGF Receptor)IBA 07/2015
1	Tyrosine Kinase InhibitorsIBA 07/2015
1	dacomitinibIBA 07/2015
1	veliparibIBA 06/2015
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 06/2015
1	ChromiumIBA 02/2015
1	SolitomabIBA 02/2015
1	neratinibIBA 10/2014
1	Excipients (Suspending Agents)IBA 07/2013
1	Temozolomide (Temodar)FDA LinkGeneric 06/2013
1	GuanineIBA 06/2013
1	Carmustine (FIVB)FDA Link 06/2013
1	laromustine (VNP40101M)IBA 06/2013
1	MethyltransferasesIBA 06/2013
1	Alkylating AgentsIBA 06/2013
1	NucleotidesIBA 02/2013
1	CreatinineIBA 09/2012

Therapy/Procedure

24	Drug Therapy (Chemotherapy) 01/2017 - 09/2005
17	Therapeutics 01/2020 - 09/2005
13	Immunotherapy 05/2012 - 01/2009
3	Neoadjuvant Therapy 12/2015 - 04/2007
3	Hysterectomy 07/2015 - 01/2003
3	Cytoreduction Surgical Procedures 02/2013 - 04/2007
2	Salpingo-oophorectomy 01/2020 - 01/2017
2	Activities of Daily Living (ADL) 01/2017 - 06/2015
1	Palliative Care (Palliative Therapy) 01/2022
1	Drug Tapering 01/2017